Optical waveguide and method of fabrication thereof

ABSTRACT

Disclosed is an optical waveguide, for transmitting a guided optical light beam having a wavelength &gt;180 nm, including a core for guiding light made of a first material having a first index of refraction, and a cladding including a thermoplastic elastomer, the innermost layer of the cladding having a refractive index smaller than the refractive index of the outermost layer of the core. Also disclosed is a medical device and waveguide sensors including the optical waveguide, as well as a method of fabrication of the optical waveguide. The method is based on the realisation of a full thermoplastic elastomer preform or a preform having a central aperture. Before or after elongating the preform to a predetermined length and a predetermined lateral dimension, the core of the preform is filled and hardened so as to provide such optical waveguide. Also described is a 3D printing method to realize the preform.

TECHNICAL FIELD OF THE INVENTION

The present invention relates to the field of optical waveguides. The present invention more specifically relates to flexible optical waveguides such as optical fibers or flat waveguides that may be used advantageously in applications and devices wherein it is difficult to provide light to a distant target and in which the light path may be tiny, present short curvatures and/or complex shape. The invention relates to flexible optical waveguides, that are biocompatible and stretchable and are based on the use of elastomers. The invention proposes a solution to applications wherein breakage of an optical waveguide would have dramatic consequences.

BACKGROUND OF THE INVENTION

Optical waveguides constitute means to provide light to a distant target and may be deployed over long lengths and through narrow spaces and possibly harsh environments. Optical waveguides in the form of fiber optics, fiber bundles or flat waveguides have been developed for a wide range of applications such as telecom, industrial and medical applications. In the case of telecom applications, the focus has been put into processes that allow to provide extremely low absorption over very long lengths, and mainly in the infrared. Other applications such as industrial machines or medical application usually do not have this requirement but have other requirements such as their mechanical properties or also compatibility requirements which are mandatory in chemical, bio-chemical or medical environments. In the case of medical implants for example, the bio-compatibility is a main requirement. This bio-compatibility is mostly also linked to other requirements such as mechanical security requirements.

For example, glass optical fibers for human implants face many difficulties as biocompatibility or breakability that can be dramatic in such applications. Furthermore, implants fabrication often needs highly flexible optical waveguides because of the complex fabrication steps of the implants.

Most existing optical waveguides are based on glass or plastic fibers and are not suitable for some medical applications such as implants.

Several attempts have been made in the past to realize optical fibers having improved mechanical properties and/or their medical or biochemical compatibility. For example, polyurethane (PU) in optical fibers field has been widely used in the coating design and the fiber optic tubing for cable production.

Several solutions have been proposed to improve the mechanical properties of bent fibres. For example, documents JPS59111952 and WO2003091178A2 propose to use polyurethanes to increase the adhesivity of the coating on the glass fiber and to protect the fibre from the micro-bending effects. PU has also been used to reinforce optical fibers in order to increase their corrosion and weather resistance in aerial optical cables, as described in CN107589507. Also, the use of PU for better resistance of optical fibers for medical applications has been described in for example CN206431340. Also, the use of PU in complex coating structures in order to correct the defects on primary coatings has been proposed in US2013243948.

In the field of fiber-optic protection-tubing applications, which deals with the fabrication of optical cables, polymers such as PU has been proposed in CN203275734, solely as an additional component to increase the cable flexibility.

Other documents in the field of optical fibres propose the use of PU as unclad optical fibres. For example, U.S. Pat. No. 4,915,473A discloses a pressure sensor by using a PU fiber whose optical transmission is inversely proportional to the pressure applied on it. Also, US20080089088A1 describes to use an unclad PU fiber to produce a side scattering for lightning and decorative applications.

Flexible optical fibers for in-vivo use in the tissue of a living mammal is described in U.S. Pat. No. 4,893,897. The document U.S. Pat. No. 4,893,897 describes a fabrication process in which two materials, such as polystyrene and aliphatic PU, are used to produce the core and the cladding of the fiber. The process is based on the melting and co-extruding of the two materials to produce a fiber-like preform which is finally drawn to the required final optical fiber dimensions. A main constraint of the fabrication of U.S. Pat. No. 4,893,897 is that the cladding material must have a melt viscosity lower than the one for the core.

Another document JP 62269905 describes how to produce a flexible optical fiber by injecting a liquid PU resin onto a hollow flexible fiber and then by polymerizing this liquid resin with a UV light. The photocurable liquid resin is for example polyurethane poly (meth) acrylate alone but could also be a monovinyl compound such as alkyl (meth) acrylate or other materials. For the hollow fiber production, the materials used were polytetrafluoroethylene, ethylene-vinyl acetate copolymer, vinyl chloride resin, and other kind of materials. The hollow fiber must be extruded by using a concentric annular shaped die. Then the liquid resin is pushed on one side and sucked by using a vacuum pump on the other side of the hollow fiber. The polymerization of the liquid core is performed by UV light. The hollow fiber production generates very low-quality surfaces that leads to huge absorption effects and so to unacceptable optical transmissions.

Early use of optical silicone to produce optical fibers was described in the document JPS5447667 that describes a glass core covered with a silicone cladding layer. The use of silicone as a coating of glass optical fibers is described in several documents such as JPS6230152 and JPH01286939, CN108977069. Even with a silicone cladding these fibers remain unacceptable for several applications such as medical implants.

Polymer fibers such as silicone fibers have been described in for example U.S. Pat. No. 5,237,638A. The fabrication of such polymer fibers is realized by dipping an extruded core into a cladding solution and then by curing the cladding. Liquid silicone can be used to produce fluid light guides, as described in U.S. Pat. No. 5,692,088A. Such liquid silicone waveguides use a flexible tube with a specific film fixed at the internal surface to play the cladding role while the core is a liquid polymer as a fluid silicone. This technique can be used to produce liquid core flexible catheters for laser ablation, as described in U.S. Pat. No. 9,700,655B2. Silicone light guides use non-curable liquid silicone and the cladding is realized by a specific treatment on the internal tube surface and the guide sizes are on another order of magnitude. Such optical fibers are limited to cores that have a large lateral cross section and the production process is difficult to reproduce relative to the required optical properties. Also, these kinds of optical fibers are only used for light delivery systems where the core diameter is less important. For sensing applications, a single-mode operation is more suitable.

Highly stretchable optical fibers are described in US2012244143 and CN107907484. The document US2012244143 proposes the use of silk while the documents CN107907484 and US2016177002 describe the use of hydrogel. Approaches based on silk or hydrogels are not useful for different applications or configurations such as the use of them to interrogate optically resonating cavities such as Fabry-Perot cavities arranged at the end of a waveguide.

There is thus a need for improved waveguides, such as optical fibers, because existing waveguides that are based on glass or plastic fibers are not suitable for a wide range of applications, such as implants or other medical applications.

SUMMARY OF THE INVENTION

The inventors of the present invention have found solutions to the above-discussed problems by providing optical waveguides, such as optical fibers, having a cladding made of a thermoplastic elastomer (TPE) such as a polyurethane. The fabrication process of the fibers and waveguides of the invention provides a wide range of advantages such as the decrease of the inherent complexity of optical waveguide production to a level where implant manufacturers could, at least partially, produce their own optical waveguides.

More precisely the invention is achieved by an optical waveguide, comprising a core layer, defining a longitudinal axis Z, and a cladding layer surrounding said core layer. The core layer and the cladding layer are configured to transmit along said longitudinal axis Z a light beam having a wavelength greater than 180 nm. an outermost layer and said cladding (20) comprising at least an innermost layer in contact with the outermost layer of the core. The outermost layer of the core is made of a material having a first index of refraction. The innermost layer of the cladding is made at least partially of a thermoplastic elastomer (TPE) having a second index of refraction (n2) being smaller than said first index of refraction (n1).

In an embodiment said at least one layer of thermoplastic (TPE) is one of: a styrenic block copolymer (TPE-s), a thermoplastic polyolefin elastomer (TPE-o), a thermoplastic Vulcanizate (TPE-v or TPV), a thermoplastic polyurethane (TPU), a thermoplastic copolyester (TPE-E), a thermoplastic polyamide (TPE-A) or a not classified thermoplastic elastomers (TPZ), In an embodiment the core I is made of a polymer, possibly silicone.

Preferably said thermoplastics is a thermoplastic as defined according to the ISO norm 18064.

In an embodiment said cladding layer comprises at least one additional layer of thermoplastic (TPE) made of: thermoplastic polyurethane (TPU), a styrenic block copolymer (TPE-s), thermoplastic polyolefin elastomers (TPE-o), thermoplastic Vulcanizate (TPE-v or TPV), thermoplastic copolyester (TPE-E), thermoplastic polyamides (TPE-A) or not classified thermoplastic elastomers (TPZ).

In embodiments the waveguide is an optical fiber, possibly a monomode optical fiber. In variants, the optical waveguide has a first lateral side having a first width W1 and a second side having a second width W2 larger than said first width W1, said widths W1, W2 being defined in any lateral cross section, defined in a plane (X-Y) orthogonal to said longitudinal axis Z.

In an embodiment, the core layer is made at least partially of: a thermoplastic polyurethane (TPU), a styrenic block copolymer (TPE-s), a thermoplastic polyolefin elastomer (TPE-o), a thermoplastic Vulcanizate (TPE-v or TPV), a thermoplastic copolyester (TPE-E), a thermoplastic polyamide (TPE-A) or not classified thermoplastic elastomers (TPZ). In a particular realization the core layer may have an index of refraction of smaller than 1.3, or smaller than 1.2 or smaller than 1.1. In an advantageous embodiment the inner surface of said cladding layer may comprises a metallic and/or dielectric layer arranged to reflect light that is incoupled into said core layer. Such a reflecting layer may be used for optical waveguides in which the core layer is not solid, such as an oil layer.

In embodiments the optical waveguide is configured to guide less than 100 modes, preferably less than 20 modes, more preferably less than 5 modes, defined in at least one longitudinal plane (X-Z, Y-Z). This is achieved by providing core layers that have smallest diameters of less than 10μ, or less than 5 μm, or less than 2 μm, the number of modes depending, as well known of the wavelength of the guided light into the core of the optical waveguide. In variants, optical waveguide is a tapered optical waveguide having at least two different cross sections. Tapering optical waveguides have an advantage in for example medical instruments wherein an optical waveguiding tip has to be provided that has a very small diameter to its end portion.

In embodiments the optical transmission (T0) of the waveguide is greater than 50%, for incoupled light having wavelengths between 180 nm and 25 μm, said optical waveguide having a length smaller than 1 m, preferably smaller than 0.5 m, more preferably smaller than 0.25 m. In variants, optical transmission (T0), is greater than 80%, preferably greater than 90% for incoupled light having wavelengths between 300 nm and 5 μm, preferable between 350 nm and 2 μm, even more preferably between 400 nm and 700 nm. The transmission is function of the material used and its possible doping, the wavelength of the guided light and the length. These parameters are chosen in function of the application for example the required dimensions that are available in a chirurgical device to be used for example with IR, visible or UV light.

In advantageous embodiments the optical waveguide is configured to be elastically stretchable up to at least 10%, preferably at least 20%, more preferably at least 30% of its length (L) and so that, after having been stretched, the optical transmission (T2) remains at least 90% of the transmission (T0) of the optical waveguide before being stretched. Stretchable waveguides are particularly useful in instruments or places wherein not much place is available and wherein it may be required to bend and/or stretch the optical waveguide.

The invention relates also to an optical waveguide bundle comprising at least three optical waveguides.

The invention relates also to a medical device comprising at least one optical waveguide of the invention. The medical device may be a cochlear implant. In another aspect the invention relates also to an optical sensor comprising at least one optical waveguide of the invention and an optical cavity sensor head arranged to said optical waveguide, the sensor head comprising an optical cavity closed by flexible membrane.

The invention is also achieved by a method of fabrication of an optical waveguide as described and comprises the steps (A-D) of:

-   -   A) realizing a hollow preform made of a thermoplastic elastomer,         preferably a thermoplastic polyurethane (TPU);     -   B) Filling the hole of said hollow preform so as to produce the         core part of the preform and provide a filled preform;     -   C) reducing the diameter of said preform and elongating said         preform to obtain an optical waveguide having a predetermined         length L and a predetermined cross section.

In an embodiment, the material of said the core part is a thermoplastic (TPE) chosen among one of: thermoplastic polyurethane (TPU), a styrenic block copolymer (TPE-s), thermoplastic polyolefin elastomers (TPE-o), a thermoplastic Vulcanizate (TPE-v, TPV), a thermoplastic copolyester (TPE-E), a thermoplastic polyamide (TPE-A) or not classified thermoplastic elastomers (TPZ), said thermoplastics being defined according to the ISO norm 18064.

In an embodiment, step B and C are replaced by the steps B′ to D′:

-   -   B′) reducing the diameter of said preform and elongating said         preform until a capillary is formed having a predetermined         length (L) and a predetermined cross section, said capillary         having a central opening having a predetermined cross section;     -   C′) introducing liquid silicone into the central opening of said         preform;     -   D′) polymerising said liquid silicone so as to form an optical         waveguide having a core being made of polymerised liquid         silicone;

In an embodiment steps C′ and D′ are replaced by the steps E′ to G′:

-   -   E′) introducing liquid silicone during said step B′ of reducing         the diameter of said preform;     -   F′) while reducing the diameter of said preform keeping said         liquid silicone in a liquid state until a predetermined         length (L) and a predetermined cross section of a precursor         optical waveguide is obtained;     -   G′) thermal polymerising said liquid silicone and said capillary         so as to form an optical waveguide.

In an embodiment the steps B′, C′ and D′ are replaced by the steps H′ to J′:

-   -   H′) after said step A, introducing a liquid polymer into the         central aperture of said hollow preform;     -   I′) reducing the diameter of the preform filled with liquid         polymer and elongating said filled preform until a capillary is         formed that is filled with liquid polymer, said capillary having         a predetermined length (L) and a predetermined cross section;     -   J′) polymerising said liquid polymer by applying UV light. In a         variant said liquid polymer is liquid silicone or liquid         siloxane.

The invention is also achieved by method of fabrication of an optical waveguide by realizing first a complete preform by a 3D technique comprising the steps (A″-B″) of:

-   -   A″. realizing a preform made entirely by a 3D printing         technique, said preform comprising a core part which will form         the core of the optical waveguide and an outer part which will         form the cladding of the optical waveguide,     -   B″. elongating said preform to obtain an optical waveguide         having a predetermined length L and a predetermined cross         section.

In an embodiment, the core part and the outer part of the preform are realized by 3D printing of successive layers, each of the successive layers comprising a central portion and an outer portion, the central portion having, at least to its side of said outer portion, a first index of refraction n1, said outer portion being made, at least to its side of said inner portion, at least partially of a thermoplastic elastomer (TPE) having a second index of refraction n2 being smaller than said first index of refraction n1.

In an advantageous embodiment the 3D system may be provided with a X and Y and Z displacement mechanism of the nozzle or nozzles, having a position precision of less than 10 μm, possibly less than 5 μm, possible having a precision of less than 2 μm. In advantageous variants, the volume deposition speed of the TPE filament, preferably a TPU filament, may be greater than 10 mm³/s, possibly greater than 24 mm³/s.

In an embodiment, said central portion and said outer portion of the successive layers are made, at least partially, of a thermoplastic elastomer (TPE) chosen among a thermoplastic polyurethane (TPU), a styrenic block copolymer (TPE-s), a thermoplastic polyolefin elastomer (TPE-o), a thermoplastic Vulcanizate (TPE-v, TPV), a thermoplastic copolyester (TPE-E), a thermoplastic polyamide (TPE-A) or a not classified thermoplastic elastomer (TPZ).

In variants the at least two of said successive layers are different shaped layers or layers having a different material composition.

In embodiments at least one additional layer is arranged to said preform, said additional layer being made of a thermoplastic elastomer (TPE) layer chosen among a thermoplastic polyurethane (TPU), a styrenic block copolymer (TPE-s), a thermoplastic polyolefin elastomer (TPE-o), a thermoplastic Vulcanizate (TPE-v, TPV), a thermoplastic polyurethane (TPU), a thermoplastic copolyester (TPE-E), a thermoplastic polyamide (TPE-A) or a not classified thermoplastic elastomers, (TPZ), said thermoplastic elastomer being defined according to the ISO norm 18064.

The invention is also achieved by the use of the optical waveguide of the invention in association with a chirurgical instrument during a chirurgical operation. In variants said use may be made for the tracking of the localisation of the position of said chirurgical instrument and/or the tracking of optical properties of tissues in the neighbourhood of the tip of said chirurgical instrument.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 shows an optical waveguide of the invention;

FIG. 2 shows a longitudinal cross section of a waveguide of the invention illustrating its optical acceptance angle and the angle of an outcoupled light beam;

FIG. 3 shows a flat optical waveguide according to the invention;

FIG. 4 shows a tapered optical fiber of the invention;

FIG. 5 shows a lateral cross-section of a fiber bundle comprising optical fibers according to the invention;

FIGS. 6-9 show exemplary cross sections of different types of optical fibers having at least two light guide cores imbedded in a polymer cladding according to the invention;

FIG. 10 illustrates some steps of the fabrication of an optical waveguide of the invention;

FIG. 11 illustrates a hybrid preform that may be used to realize a Fan-In/Fan-out optical component according to the invention;

FIG. 12 illustrates a sensor head comprising an optical cavity that comprises an outer membrane, said cavity being arranged by an outer tube on an optical fiber of the invention;

FIG. 13 illustrates an optical fiber of the invention comprising a lateral incoupler grating and a lateral outcoupler grating;

FIG. 14 illustrates a cochlear implant comprising an optical fiber of the invention;

FIG. 15 shows an example of a portion of a preform comprising two holders to make a fan-in/fan-out optical component;

FIG. 16 shows a portion of a preform comprising two holders to make a fan-in/fan-out optical component, the two holders comprise a plurality of wires to be removed after injection of a TPE polymer;

FIG. 17 illustrates a preform after overmolding of a TPE polymer of the wires that are between the two holders of the arrangement of FIG. 16 ;

FIG. 18 illustrates the demolding of a hybrid multicore fiber and fiber bundle preform after the injection of a TPU layer as cladding layer;

FIG. 19 shows a hollow shaped preform made of TPU;

FIG. 20 shows an end face of an optical fiber having a core and cladding made of two types of TPU and realized by the method of the invention;

FIG. 21 illustrates a multifiber Fan-in/Fan-out platform realized by using the mold of FIG. 16 and FIG. 17 ;

FIGS. 22-23 show experimental results obtained with an optical fiber according to the invention;

FIG. 24 illustrates a far-field distribution of guided modes of a waveguide of the invention that has been elongated at different percentages;

FIG. 25-27 show complex-shaped cross sections of a preform of the invention, realized by a 3D printing technique;

FIG. 28 illustrates the realization, by 3D printing, of a full preform by depositing successive layers that comprise a core portion and an outer portion so as to form a full preform at the end of the 3D printing process.

DETAILED DESCRIPTION OF THE INVENTION

The present invention will be described with respect to embodiments and with reference to the appended drawings, but the invention is not limited thereto. The drawings described are only schematic and are non-limiting. In the drawings, the size of some of the elements may be exaggerated and not drawn on scale for illustrative purposes. The dimensions and the relative dimensions do not correspond to actual reductions to the practice of the invention.

As used herein, the term “optical waveguide”—defined also as waveguide—used herein encompass all types of homogeneous or non-homogeneous and/or tapered optical waveguides such as monomode and multimode fibers but also monomode and multimode flat optical waveguides and also waveguide bundles that comprise a plurality of optical fibers or flat optical waveguides or a mix of them. Waveguides 1 have a longitudinal axis which is defined as a central virtual axis of the waveguide 1 defined in the direction of the guidance of an optical light beam 100 in the waveguide 1. Optical guidance may be performed by total internal reflection (TIR) or by using reflecting or diffracting layers or structures. In the case of monomode waveguides only one mode is guided through the core of the waveguide. Said virtual axis defines a Z-axis and two orthogonal axes X, Y or directions to said Z-axis. Lateral cross sections herein are cross section defined in a X-Y plane. Longitudinal cross sections are defined in a plane comprising said Z-axis.

The terms “cladding” and “core” are also defined as cladding and core layers and may be layers that do not have a circular cross section. This is valid as well for the core and cladding of the preform as described, as for the core and cladding realized optical waveguides.

The types of the optical waveguide 1 of the invention will be chosen according to the type of application or geometric constraints and the geometrical and working temperature requirements of the device wherein optical waveguide 1 is implemented and are typical, but not exclusively the following choices:

-   -   single fibers: for transmitting intensity, polarisation and         spectral information;     -   fiber bundles: for transmitting images and illuminating light         beams;     -   multi-core optical waveguides such as multi-core optical fibers;     -   flat waveguides: for transmitting intensity, polarisation and         spectral information, as well as the transmission of images and         illumination light beams;     -   Fan-in/Fan-out optical devices.

The use and optical functioning of optical waveguides 1, defined also herein as waveguides, such as optical fibers 1 and optical fiber bundles 300 are well known to the skilled person in the field of guided optics and are not described further here. It is also known how to configure an optical fiber arrangement suited for illuminating an object and collecting reflected or transmitted light by such an object. The invention proposes optical waveguides such as optical fibers and a fabrication procedure of these fibers. As described further in detail, one of preferred fabrication methods includes a realisation of a thermoplastic elastomer (TPE), hollow shaped preform 204, a such as thermoplastic polyurethane (TPU) preform, that may be thermally drawn to obtain a highly flexible TPU capillary 2000. Waveguides 1 of the invention are realized by either filling a hollow shaped preform 204 with a polymer and pulling them to obtain a thin waveguide 1, or by first realizing a solid capillary and filling it with a liquid polymer. Different ways of the curing of the liquid polymer of the core 10 are described further. The liquid to be used to form the core 10 of the waveguide 1 is preferably silicone, or siloxane.

In a first aspect the invention proposes a new biocompatible and highly stretchable optical waveguides 1 by using low-cost, biocompatible and optically transparent materials with a much more reduced multimode behaviour. The invention relates to the use of a thermoplastic elastomer (TPE) for the cladding of the optical waveguide 1 and the preform to make it. The cladding 20 of the waveguide 1 of the invention is composed at least partially of a thermoplastic elastomer (TPE), preferably a TPU elastomer. The cladding is made from a hollow preform 204 composed at least partially, or entirely, of thermoplastic polyurethane. As described further the core 10 of the optical waveguide may be another type of TPE than the one used for the cladding or may be a liquid silicone that is polymerized in a realized capillary shaped cladding. The invention is not limited to waveguides having a solid core. The optical waveguide 1 may also be a hollow waveguide consisting solely of a capillary made of an elastomer composed at least partially of thermoplastic polyurethane (TPU) and having a coating of it internal surface, such as a reflecting metallic or dielectric coating as described further herein.

It is understood that the optical waveguides 10 of the invention may be arranged in a wide variety of forms and geometries or may be arranged in any configuration in a medical device 2. In a first aspect the invention relates to an optical waveguide 1, comprising a core layer 10, defining a longitudinal axis Z, and a cladding layer 20 surrounding said core layer 10, said optical waveguide 1 having an incoupling surface 31 for incoupling a light beam 110 into said core layer 10 and an outcoupling surface 51 for outcoupling light 120 out of said core layer 10, said core layer 10 and said cladding layer 20 being configured to transmit along said longitudinal axis Z a guided light beam 100, through said core layer 10 and from said incoupling surface 31 to said outcoupling surface 51, said guided light beam 100 having a wavelength greater than 180 nm. In all the embodiments of the invention the cladding layer of the optical waveguide 1 is composed, at least partially, of thermoplastic elastomer (TPE). which is a thermoplastic rubber. TPE is a thermoplastic elastomer and is part of a class of copolymers or a physical mixture of polymers, usually a plastic and a rubber, that consists of materials with both thermoplastic and elastomeric properties. Thermoplastics components are relatively easy to manufacture, for example by injection moulding Thermoplastic elastomers present both the advantages of rubbery materials and plastic materials. The benefit of using a thermoplastic elastomer, such as TPU, as a material for at least the cladding of the optical waveguide 1 of the invention is the surprising ability to stretch to moderate elongations and return to its near original shape creating a longer life and better physical range than other material. The principal difference between thermoset elastomers and thermoplastic elastomers, such as TPU, is the type of crosslinking bond in their structures. In fact, the crosslinking property is a critical structural factor which imparts the high elastic properties of the optical waveguide of the invention. TPE is well known and not further described here.

There are six generic classes of commercial TPEs (designations according to the ISO norm 18064):

-   -   styrenic block copolymers, TPS (TPE-s);     -   thermoplastic polyolefin elastomers, TPO (TPE-o);     -   thermoplastic Vulcanizates, TPV (TPE-v or TPV);     -   thermoplastic polyurethanes, TPU (TPU);     -   thermoplastic copolyester, TPC (TPE-E);     -   thermoplastic polyamides, TPA (TPE-A);     -   not classified thermoplastic elastomers, TPZ.

Herein, the cladding is at least partially composed of a TPE but other different TPE materials may be combined for realizing the cladding layer. In a preferred embodiment the entire cladding layer is made of TPE, preferably entirely made of TPU which is particularly well suited for certain applications such as medical devices.

All mentioned TPE may be used to realize the preform 200 and the optical waveguide 1 of the invention. TPU is the preferred choice among these TPE materials. The reason is that it has the best combination of thermoplastics and rubbers (thermosets) for the desired properties of the optical waveguide 1 of the invention, as described further in detail. The cladding layer 20 may be a homogenous layer but may also be made of at least two sections that have a different layer composition. The cladding may be made by at least one layer that is made of a homogenous TPE layer but may also be made by a non-homogenous TPE layer. In variants the TPE layer may comprise at least to one of its sides at least another layer made of TPE. This may be used to realize for example a gradient index optical waveguide 1 comprising a plurality of TPE layers with different refractive indexes. Said another TPE layer may be a non-homogenous layer which may have a diameter that varies along the length of the cladding layer. As further described such a non-homogeneous layer may be an external layer that has a mechanical function and which is incorporated to the cladding of the waveguide and may be used for improved mechanical adherence or clipping or gripping or sliding into a device.

The core layer 10 is made of a first material having a first index of refraction n1, and the cladding layer 20 is made of at least one layer composed at least partially of TPE, for example TPU, having a second index of refraction n2 that is smaller than said first index of refraction n1.

In a specific case the optical waveguide 1 is a capillary made of at least one cladding layer that comprises an internal reflection layer and the core layer 10 may be air or vacuum or may be a liquid, such as oil. In such cases the waveguide comprises a closure at each end of the capillary structure.

The values of refractive indexes of the core and/or cladding layers 101, 20 can cover a broad range for both materials for example n2 may be between 1.49 and 1.57 and n1 may be between 1.52 and 1.60. It is understood that, in a preferred embodiment the core 10 and cladding 20 of the optical waveguide may be uniform layers that have a uniform refractive index n1, respectively n2. The cladding is in contact with the core. As well the cladding 20 as the core 10 may comprise different layers that are in contact. The inner layer of the cladding 20 is in contact with the outer layer of the core 10 to ensure total reflection. The core 10 and cladding 20 may be composed of a succession of layers that have different discrete refractive indexes. The core and/or cladding may have a gradient index that varies continuously over the diameter of the core 10 and/or cladding 20, which may be realized by doping the deposited polymers during their manufacturing. Anyhow, the refractive index of the outermost layer of the core 10 has a refractive index that is higher than the refractive index of the innermost layer of the cladding 20, said innermost and outermost layers being in contact.

The limitation of the useful length of the proposed optical waveguide 1 may be the penetration length of the core material, such as in the case of the use of a liquid silicone or another TPU composition as the core material to be introduced into a TPE capillary as further described in the method section. TPU is a preferred choice among the TPEs as it possess rubber-like elasticity, high tear and abrasion resistance, high elongation at break as well as excellent thermal stability. In addition to this, TPU is also resistant to oils, greases, and a variety of solvents. TPU is also the firmest of TPE and may be printed by 3D techniques as further described. The use of TPU allows to fabricate complex internal and external structures of the optical waveguide 1. Additionally, TPU may be provided in a huge range of colours, has low shrinkage and is excellent for applications wherein vibration damping, and impact resistance are important. Waveguides 1 made in TPU are particularly suited for medical applications because of these properties. For applications wherein such stringent requirements are not mandatory, the calling and possibly also the core of the waveguide 1 may be made by another type of TPE. Different fabrication methods are possible that are described further, and each variant of other method allows to achieve different geometries and different lengths in function of the application and so the required intensity throughput or the required intensity variations. Nevertheless, a typical optical waveguide 1 is an optical fiber having a fiber length of around 10 cm, for example in the case of medical implants, but it may longer. For example, a length of 10 cm would be enough for an organ-scale distance that is over 10 cm for humans [Ref. 5].

In preferred embodiments, the lineal loss of the optical waveguide 1 does not exceed 0.5-1 dB/cm, which ensures an overall loss of maximum 10-20 dB for a round trip on a 10 cm long waveguide. The bending losses are of high importance in applications as cochlear implants [3] where the waveguide 1 must be arranged on tight radii as we can found inside a cochlea (1-2 mm at the far end). However, these radii are progressive and the waveguide 1 may be placed through places having very short bending radii only over a few millimetres. In order to provide some margin on the final retrieved signal coming from a resonating cavity at a fiber tip for example, it is essential that the waveguide 1 has less than 5 dB loss on a round trip base for a bending radius of about 5 mm over a fiber length of 30 mm that corresponds to an average cochlear length. Obviously, this constraint is driven by the waveguide attenuation itself. If the fiber attenuation is much lower than the 0.5-1 dB/cm specified above, then the margin available for the bending loss will be higher.

Typical attenuation values are 0.79 dB/cm at 1550 nm and 0.46 dB/cm at 1300 nm. At 633 nm, attenuation values are lower 0.79 dB/cm at 1550 nm and 0.46 dB/cm at 1300 nm So, optical waveguide lengths of more than 2 m may be used. Experimental data have shown that the optical waveguide 1 of the invention has a lower attenuation in the visible part of the spectrum than in the infrared part of the spectrum.

In a preferred embodiment, the optical waveguide 1 is a monomode or a multimode fiber, as illustrated in FIG. 1 . The lateral cross section 30 of the core 10 and the cross section 40 of the cladding 20 may be uniform over the length of the waveguide 1, but may also vary as illustrated in FIG. 4 .

In an embodiment, illustrated in FIG. 3 the optical waveguide 1 has a first lateral side 1 c having a first width W1 and a second side 1 b having a second width W2 that is larger than said first width W1, said widths W1, W2 being defined in any lateral cross section, defined in an plane X-Y orthogonal to said longitudinal axis Z. FIG. 3 shows a flat optical waveguide 1 having a rectangular shaped cross section, but other cross sections may also be possible, such as elliptical shaped cross sections, or trapezium shaped cross-sections.

In an embodiment, illustrated in FIG. 4 , the optical waveguide 1 is a tapered waveguide 1, having a tapered form in at least one plane comprising said longitudinal axis Z. FIG. 4 illustrates a varying shape and/or dimension of lateral cross sections 42, 44.

In an embodiment, said core layer 10 is made of a polymer. This polymer may be silicone.

In variants the core layer may be a liquid. This may be realized by providing a capillary that has a very small core diameter so that the liquid remains trapped inside the optical waveguide 1. In a variant the input and output areas of a waveguide having a liquid core may have a window to close of the liquid core so that the liquid remains inside the waveguide 1.

In an embodiment a reflecting layer may arranged between said core layer 10 and said cladding layer 20, said reflecting layer being arranged to provide inside said core layer 10, total reflection and guidance of incoupled guided light into said core layer 20. Said reflecting layer may be a metallic layer or a dielectric layer or a combination of them.

In an embodiment the optical waveguide 1 is an optical fiber wherein said core layer 10 and said cladding layer 20 are configured to guide a number of modes less than 100, preferably less than 20, more preferably less than 5. In an embodiment the optical waveguide 1 is a monomode fiber.

In an embodiment the optical waveguide 1 is configured to guide less than 100 modes, preferably less than 20 modes, more preferably less than 5 modes, defined in at least one longitudinal plane X-Z, Y-Z.

In an embodiment the optical waveguide 1 is a tapered optical waveguide having at least two different cross sections 42, 44.

The optical waveguide 1 has an optical transmission T0, defined as the ratio I2/I1 of the intensity I2 of the outcoupled light 120 to the intensity I1. In an embodiment the optical waveguide 1 has a practical length smaller than 2 m, preferably smaller than 0.5 m, more preferably smaller than 0.25 m. and the intensity I2 of the outcoupled light 120 may be greater than 10%, preferably greater than 30% than the intensity T0 of the incoupled light 110, for incoupled light having wavelengths between 180 nm and 25 μm.

In an embodiment a useful length of the optical waveguide 1 has an optical transmission that is greater than 80%, preferably greater than 90% for incoupled light having wavelengths between 300 nm and 5 μm, preferable between 350 nm and 2 μm, even more preferably between 400 nm and 700 nm. In the case of medical implants for example. said useful length is typically 10-20 cm.

In an embodiment the optical waveguide 1 can be elastically stretched up to at least 10% of its length L and so that, after having been stretched, the optical transmission T2 remains at least 50%, preferably at least 70%, even more preferable at least 90% of the transmission T0 of the optical waveguide 1 before being stretched.

One of the essential features of the optical waveguide 1 is that it may be stretched while maintaining substantially its optical guidance properties. In the case of a hollow core waveguide 1 made of TPU the core 10 is air or vacuum, and an elongation of 600% is possible before breakage of the waveguide 1. In the case of an optical waveguide 1 having a core 10 made of silicone the possible elongation before rupture may be similar depending on the adherence properties of the core layer 10 with the cladding layer 20. The rupture limit may also depend on the elongation properties of the core layer because, depending on the chosen core material layer, the core layer may be damaged or ruptured before the damaging of the cladding layer. Typical silicone core layers may have an elongation of up to 50% before rupture.

In an embodiment an adherence or an antifriction layer may be provided at the inner surface of said capillary 2000 before introducing said liquid core material. This provides ways to improve the breakage limit or possible mechanical damages to the waveguide 1 for example in situations of small curvature radii and/or high traction forces.

In an advantageous embodiment the optical waveguide 1 may be made, at least partially, electrically conductive, which is possible by providing an electrical conducting TPU material for the preform and so for the core and/or cladding of the optical waveguide. As described further, the 3D printing technique may also allow to imbed in the full or hollow preforms 200, 204, and thus the optical waveguide 1, at least one electrical and conductive wire which may be very useful in some medical devices. In variants the preforms 200, 204 may be doped preforms or preforms comprising a powders, such as an electrical conductive powder or substance. This may be useful to provide optical waveguides 1 that may be partially electrically or thermally conductive. In variants, only the cladding 20 of the optical waveguide 1 may be made electrically or thermally conductive.

The invention is also achieved by an optical waveguide bundle 300, illustrated in FIG. 5 comprising at least three optical waveguides 1 a, 1 b, 1 c as described. In a variant 7 optical fibers 1 may be arranged into such a fiber bundle 300 that comprises an outer mantle 302 and an inner filling material 304.

In embodiments illustrated in FIGS. 6-9 an optical waveguide 1′, 1″, 1′″, 1″″ may comprise a plurality of core layers 10′, 10″, 10′″, 10″″.

In embodiments the cladding layer may comprise at least two layers, of which at least one layer comprises a TPU polymer or is made entirely of a TPU polymer. In embodiments the cladding layer may comprise at least five layers, allowing to provide for example a gradient index waveguide. In variants, the core 10 may also be made of at least two different layers, both may be a TPU layer or another type of TPE layer.

In embodiments the optical waveguide (1) may be a polarization maintaining waveguide (1). This may be realized by incorporating polarisation substances in the preform, possibly added by 3D printing as described herein.

It is understood that the optical waveguide 1 of the invention is not limited to only a waveguide 1 comprising a core layer 10 and a cladding layer 20. As well the core layer 10 and/or the cladding layer 20 may comprise structured portions that have an optical function. A typical optical structure is a diffraction grating that may be a local diffraction grating or a distributed grating, as illustrated in FIG. 13 . Also, hologram-type structures or layers may be arranged into or on said optical waveguide 1.

In advantageous embodiments, at least a portion of said waveguide 1 is arranged according to a resonant waveguide grating (RWG). RWG's are described in for example:

-   -   A. Sharon et al.: “Resonating grating-waveguide structures for         visible and near-infrared radiation”: J. Opt. Soc. Am” vol. 14,         nr. 11, pp. 2985-2993, 1997.

RWG's are made by using a multilayer configuration and combine subwavelength gratings and a thin waveguide. A resonance occurs when incident light is diffracted by a grating and matches a mode of the waveguide. As most of the spectrum of incoupled light does not couple into the waveguide, strong spectral effects are provided in reflection and/or transmission. This to the fact that RWG's are corrugated waveguides and behave as a waveguide-grating. The use of RWG in indicia allows to provide unique optical effects that are extremely difficult to identify and to duplicate. RWG's are generally designed to have spatial periodicity shorter than the wavelength they operate with and are therefore called “subwavelength” structures or subwavelength devices. Eventually they have periodicities closed to the wavelength they are operating with and just above it. Quite often, the periods are significantly smaller than the free-space wavelength they are working with, for example a third of it. Because of their small periodicity, they do not allow various diffractive orders, which distinguishes them from much simpler diffractive optical elements (DOE).

Using RWG allows to provide unique incoupling and outcoupling optical effects, for example by providing a high incoupling and/or outcoupling efficiency or to incouple and outcouple polarized light beams more efficiently or with predetermined angles which would not be possible by using ordinary diffraction gratings such as binary diffraction gratings. RWG may be realized by embossing techniques allowing to provide cheap waveguide that have very efficient light coupling efficiencies that may depend, according to their design, particularly on specific predetermined wavelengths. In variants that are not illustrated in figures at least one of the lateral surfaces of the waveguide 1 is arranged, continuously or discontinuously, over at least 50% of its entire length, as an incoupling surface and/or an outcoupling surface. Said incoupling surface and/or an outcoupling surface may be configured as a RWG.

The invention is also achieved by optical systems or sensors comprising at least one optical waveguide 1 as described herein. In an example, a resonating cavity is arranged as a tip of the optical waveguide 1 of the invention. As a light source low-cost telecom-grade LEDs may be used to interrogate the resonating cavity. In such devices a useful fringe visibility is required in cavity lengths of around 200-300 μm.

The invention is also achieved by an optical waveguide sensor that comprises a resonating cavity 520 arranged in a tip fixed to the output end of the optical waveguide deformable diaphragm 530. The cavity 520 may have another function than a resonating effect, for example the cavity may provide, through the deformation of the membrane, a varying light intensity of the light beam that is sent back into the fiber 1. In embodiments, cavities 520 may be filled with air or a liquid, such as oil.

The invention is also achieved by a pressure sensor that comprises an optical waveguide of the invention. The pressure sensor may rely on the bending or elongation effects on the transmitted intensities of the optical waveguide as described in the experimental section further.

In embodiments the medical device is an implant to be used in cochleas. FIG. 14 illustrates a cochlea implant 600 that comprises a central portion 606 to be inserted into the ear of a human being. A mechanical guidance structure 606 is arranged to said central portion and comprises at least one optical waveguide 1 according to the invention.

In advantageous embodiments the medical device may comprise at least one optical waveguide 1 of the invention to provide a UV-light beam to a predetermined location, for example to disinfect a location in a living body. It is generally understood that at least one extremity of the optical waveguide 1 may have a shape so that it may be used for an optical function such as the deviation or focusing or diverging of an incoming or outcoupled light beam. Said shape may be realized during the fabrication process of the waveguide 1, for example by heating the extremity so that a rounded shape is provided to an end of the waveguide.

The waveguide 1 of the invention may be used for optogenetics described in Ref.18. The invention. is related also to a device to be used in optogenetics and that comprises at least one waveguide 1 according to the invention.

The waveguide 1 of the invention may also be used to track in real-time surgical instruments, for example to give information of the localisation of the tips of the instruments or to monitor optical information at the tip of the optical waveguide at the place of a surgical intervention. The invention is therefor also related to a surgical instrument that comprises the optical waveguide of the invention.

In a second aspect the invention relates to the fabrication of an optical waveguide 1 as described before, and comprises the steps of (A, B, C):

-   -   A. Realizing a hollow-shaped preform 204, having a central         aperture 202′, made at least partially of thermoplastic         elastomer (TPE), preferably of TPU. The hollow-shaped preform         204 has an innermost layer which is a TPE elastomer having a         second refractive index n2 that is substantially, within an         error of 10% the refractive index of the cladding of the optical         waveguide 1 to be formed with the method of the invention. In         variants the whole hollow preform 204 may be made of a TPE         elastomer having a second refractive index n2;     -   B. Filling the central aperture 202′ of said hollow-shaped         preform 204 so as to produce the core part 202 of the filled         preform 200. The core part 202 has an outermost layer that is         made of a material having a first refractive index n1 that is         greater than said second refractive index. In variants the whole         core part 202 may be made of a material having a second         refractive index n2;     -   C. reducing the diameter of said preform 200 and elongating it,         until an optical waveguide 1, typically an optical waveguide is         formed having a predetermined length L and a predetermined cross         section 40, 41.

It is understood that the refractive indices of the core 10 and the cladding 20 of the optical waveguide 1 are, after the said reduction step C, within an error of 10%, substantially the same refractive index than the refractive indices of the core part respectively the wall of the hollow shaped preform 204.

In an embodiment said preform 200 in step A is made by a first injection in a mould, typically a cylindrical-shaped mould. This mould is preferably a metallic or ceramic mould. The role of the cylindrical insert is to provide a preform having a central hole 202, defined also as central aperture. FIG. 19 shows an example of a realized TPU preform 200 that comprises an outer part 204, also defined as the wall of the preform, and a central aperture 202 that is to be filled by material that constitutes the core 10 of the optical waveguide when drawn from the preform 200. Said outer part 204′ forms, when drawn, the cladding 20 of the optical waveguide and the inner part 202 forms, when drawn, the core 10 of the optical waveguide 1. In a variant a hollow preform may also be first drawn to a certain length and provide a TPE capillary to be filled with core material and polymerised.

In an advantageous embodiment said cylindrical preform 204 in step A is made in step A by a 3D printing technique.

In an embodiment the filing step B is made after step A has been executed, for example by an injection technique.

In an advantageous embodiment the step A and B is performed simultaneously by a 3D printing technique. By using such a 3D printing technique, the core and the cladding layer of the preform are built by adding successive layers. In each such layer a different PME elastomer is printed inside a layer of TPU, preferably a ring-shaped layer. TPU is a preferred choice of TPEs as it provides a layer to layer adhesion that may be printed more strongly and durable than other TPEs. The applications of the optical waveguide 1 of the invention focus on specialty waveguides such as needed for medical devices. Therefore, a slow printing speed can be allowed to realize the preform which may have a very complex shape. As the required lengths for the applications of the invention are small lengths it is acceptable that the time to process the preform 200 may be much longer than what is usually required for telecom preforms. Out of 1 preform thousands of short lengths of optical waveguides may be provided.

FIG. 28 illustrates a method of formation of a completely filled preform 200 by a 3D machine 500. In the example of execution of FIG. 28 a single nozzle 502 provides a stream 504 of polymer. In the example of FIG. 28 the core part 202 and the outer part 204′ of the preform 200 are realized by 3D printing of successive layers 200 a-200 c. FIG. 28 only shows the first 3 layers 200 a-200 c that have been formed during a 3D printing operation. Each of the successive layers 200 a-200 c comprises a central portion 202 a-202 c and an outer portion 204′a-204′c, the central portion 202 a-202 c having, at least to its side of said outer portion, a first index of refraction n, said outer portion 204′a-204′c being made, at least to its side of said inner portion 202 a-202 c, at least partially of a thermoplastic elastomer (TPE) having a second index of refraction n2 being smaller than said first index of refraction n1. In embodiments several variants to the 3D printing process may be conceived. For example, more than one central portion may be deposited during each layer step. The advantage of using a 3D printing as described here is to allow to provide complex shaped core parts and/or outer parts of the preform 200, such as illustrated in the example of FIGS. 25-27 .

In embodiments, the material of the core part 202 of the preform 200 may be thermoplastic elastomer (TPE) layer chosen among one of: a styrenic block copolymer (TPE-s), thermoplastic polyolefin elastomers (TPE-o), a thermoplastic Vulcanizate (TPE-v, TPV), a thermoplastic polyurethane (TPU), a thermoplastic copolyester (TPE-E), a thermoplastic polyamide (TPE-A) or not classified thermoplastic elastomers, (TPZ), said thermoplastics being defined according to the ISO norm 18064.

The advantages and more details on the use of TPE, preferably TPU, for the preform and optical waveguides 1 of the invention are now described in more detail.

Elastomers are based on relatively long polymeric chains having a high degree of mobility and flexibility. Those chains are linked to a network structure that prevents them to flow from each other when an external stress is applied. That configuration resides on a dual-phase material where one phase is hard and solid whilst the other one is an elastomer. The elastomeric phase will offer the elasticity of the material and the solid phase will bring the physical crosslinks keeping the strength of the material. When processing such material, two different glass transition temperatures are involved: one for the elastomeric polymer, Te, and another one to the hard phase, Th, where Th>Te. Basically, the material will need to be used between those two temperatures as for temperatures T<Te, both phases are hard and brittle and for T>Th, the material will start to be a viscous fluid. That is of importance for the production of an optical waveguides, such as optical fibers, due to the fact that weakly guiding fibers need, as a basic configuration, a step-index refractive index and hence two different polymers, such as tow different TPUs. Care needs to be taken in the choice of the two TPU materials needed to produce the step-index profile. The temperatures are usually well below the 0° C. temperature and are of less concern in the choice. However, Th will have a direct influence in the fiber drawing as one of the two polymers, for example two different TPUs, will start to melt at a lower temperature than the second one. Furthermore, the heating system, if not correctly designed, will generate a non-homogenic radial heat distribution into the preform enhancing the Te difference effect.

In an exemplary embodiment two TPUs are used to produce an optical fiber: i.e. BASF Elastollan 1185A and Ellastollan 1185 A10W having refractive indexes, nd, of 1.505 and 1.553, respectively. The processing temperatures for both TPUs are relatively similar and then offer an eased selection of the right drawing temperature.

In a typical execution, the preforms 200, 204 may be realized in a two-step injection moulding process using for example an Arburg Allrounder 170S injection machine. Said first injection is performed in a cylindrical mould having dimensions of 15 mm in diameter for 100 mm in length with a cylindrical insert in the middle along the cylinder axis. In a preferred embodiment the first step preform generates the cladding part of the fiber by using the Elastollan 1185A TPU. A second injection, using the Elastollan 1185 A10W, may be realized in order to fill the hole and produce the core part of the preform.

In embodiments the extruder of the 3D printer has a fully enclosed PTFE lined filament guide to prevent the filament from buckling during the printing process.

In variants the nozzle has an interior diameter of 0.25 mm, possibly as small as 0.1 mm. In order to provide a smooth PTE filament, preferably a PTU filament, an internal pressure system may be provided.

In order to provide precise structures in the model, the 3D system may be provided with a X and Y and Z displacement mechanism of the nozzle or nozzles, having a precision of less than 10 μm, possibly less than 5 μm, possible having a precision of less than 2 μm. In advantageous variants the volume deposition speed may be greater than 10 mm³/s, possibly greater than 24 mm³/s. Compared to rigid thermoplastics at nominal nozzle temperatures, TPU has a much lower viscosity. This allows for high intermolecular diffusion or healing during the FDM process. So, TPU is a better choice for realizing optical waveguide preforms than other polymers.

In embodiments, the filled or hollow shaped preforms 200, 204 may be made with at least one layer of TPE, preferably TPU, to which at least another layer is arranged. Such additional layer may be realized to the inner wall of the cylindrical aperture of the TPE layer or to its outside surface.

The preforms 200, 204 made at least partially of TPE, preferably TPU, may comprise a plurality of layers having a predetermined order of refractive indices so that for example a gradient index layer is provided to the core layer 10 of the optical fiber 1 when it has been realized by elongating the preform 200. Providing optical waveguides having a gradient index profile around its core 10 has several advantages relative to the propagation characteristics of a guided light beam. The gradient index profile may be adapted to control the type and number of guided modes in the optical waveguide 1.

In an advantageous embodiment the inner surface of the TPE-based preforms 200, 204, preferably a preform made in TPU, is polished to improve the smoothness of its surface in order to reduce optical losses due to the interface of the core and cladding of the produced optical fibers as commented further in detail in the experimental section.

3D printing of a full or hollow preform 200, 204 that is made at least partially of TPE, preferably TPU, allows to provide conventional step-index optical fibres and dopant distributions that would be difficult, if not impossible to achieve with standard injection techniques to fabricate optical waveguide preforms. The reason is that the geometry of each layer that is created with a 3D print process can be adapted. In a first aspect there is a benefit for realizing micro- and nanostructured optical waveguides 1 such as optical fibres. The fabrication of these fibres is limited to methods that are often only suitable for specific materials. In a second aspect the outer and inner cross sections may have a shape that is predetermined. For example, the cross section may be square or hexagonal over the entire length of the preform.

Additionally, the shape of the cross section may vary over a predetermined length of the preform. For example, the preform may have a hexagonal cross section over 80% of its length and the two extreme parts may have another cross-section shape, for example a circular shape. In variants, the preform may be made, over a first length, a first type of TPE, such as a TPU elastomer, and over a second length be made of another type of polymer, for example another type of TPE or TPU. This is made possible easily by a 3D printing technique.

In embodiments, the preform 200, 204 and so the optical waveguide 1 may have a Y-shape or any other shape presenting more than 2 branches, to provide optical waveguides 1 that may have N incoupling branches and M outcoupling branches, M being equal or greater than N. For example, a TPU based optical waveguide may have 2 incoupling sections and 4 outcoupling sections. This would be extremely difficult, if not impossible, to realize with injection techniques, to the contrary of the 3D printing technique proposed by the invention.

In other embodiments, the cladding 20 may be formed around at least one solid element, such as a solid axis, so that the waveguide is firmly attached to that element without having to glue or fix it. This avoid wrapping or fix a waveguide 1 to such an element, which may be a component of a medical device, allowing to reduce the costs.

Realizing the preform with a 3D printing technique is particularly interesting in the frame of the present invention because the optical waveguides 1 can have a particular outer and/or inner shape that allows the waveguide to be easily adapted into or on a chirurgical device. For example, the filled preform, i.e. having a cladding and a filled core, may be realized so that there is at least one longitudinal aperture in for example the cladding, allowing to fit the optical waveguide 1 onto a very thin guidance wire. In variants, the preform, and thus the final optical waveguide, may have an undulated surface in their length and/or their width.

In another aspect, by realizing a preform with a 3D printing technique one may easily make waveguides that have a donut-shaped cross section or a halter shape that comprises 2 cores. In variants hexagonally packed preforms and fibers may be realized with the 3D process. In other variants the preform and so also the manufactured optical waveguide thereof is made, at least partially, of a photonic crystal.

In yet another aspect, 3D printing of the TPE cladding, preferably a TPU cladding, and/or a filled preform realized entirely with a TPU elastomer allows to add mechanical forms and features to the outside of the formed optical waveguide, which has an interest in the mounting and fixing in narrow chirurgical instruments. For example, during the 3D printing lateral structures may be added to the preform, and thus the later realized optical waveguide, said lateral structures may be realized in for example a harder polymer. By using a 3D printing technique, at least two deposited layers may have different compositions. It would be particularly difficult to realize the above-mentioned shapes by realizing a TPU based preform with injection techniques. This is mainly due to the design complexity limitation induced by injection moulding compared to the 3D printing. Known drilling, extrusion and injection moulding or mechanical tuning of TPU based preform would be difficult and time-consuming. 3D printing of the TPU-based preform has a huge competitive advantage for realizing waveguides that have a TPU-based cladding, with possibly a TPU based core.

FIGS. 25-27 show cross sections of complex shaped preforms that may be realized by 3D printing a TPU preform 200, 204. Such preforms 200, 204 may also be made in a TPE polymer.

In a variant, a hollow shaped preform 204 is first formed and then an elongated capillary is realized that is filled with a polymer that may be different than a TPE elastomer, such as silicone. Such a method variant comprises the steps (A-D′) that are illustrated schematically in FIG. 10 :

-   -   A) realizing said hollow preform 204 made at least partially of         a TPE elastomer as described above;     -   B′) reducing the diameter of said hollow shaped preform 204 and         elongating said preform until a capillary 2000 is formed having         a predetermined length L and a predetermined cross section 40,         41, said capillary 2000 having a central opening 2002 having a         predetermined cross section 30;     -   C′) introducing liquid silicone 11 into the central opening 220         of said preform;     -   D′) polymerising said liquid silicone so as to form an optical         waveguide 1 having a core 10 being made of polymerised liquid         silicone 11 and having a predetermined length L and an outside         diameter D2. The diameter of the core is directly related to the         proportion of the outside diameter of the preform D1 and the         diameter of the aperture of the preform, because this proportion         does not change during the diameter reduction step B′;

In an embodiment step C′ and D′ are replaced by the steps E′, F′, G′:

-   -   E′) introducing liquid silicone 11 during said step B of         reducing the diameter of said preform;     -   F′) while reducing the diameter of said preform 200 keeping said         liquid silicone in a liquid state until a predetermined         length (L) and a predetermined cross section 40, 41 of a         precursor optical waveguide is obtained;     -   G′) thermal polymerising said liquid silicone 11 and said         capillary 2000 so as to form an optical waveguide 1. In variants         the capillary 2000 may be polymerised before the polymerisation         of the liquid silicone;

In an embodiment steps B′, C′ and D′ are replaced by the steps H, I, J:

-   -   H′) after said step A, introducing a liquid polymer 11 into the         central aperture 202′ of said hollow preform 204;     -   I′) reducing the diameter of the preform 204 filled with liquid         polymer 11 and elongating said filled preform 200 until a         capillary 2000 is formed filled with liquid polymer 11, said         capillary having a predetermined length L and a predetermined         cross section 40, 41;     -   J) polymerising said liquid polymer by applying UV light.

In an embodiment step said liquid polymer is liquid silicone, possibly a liquid siloxane.

In an embodiment of the method said obtained optical waveguide 1 is a multimode optical fiber. In a variant, said obtained waveguide is a mono-mode optical fiber.

In an embodiment said obtained waveguide is an optical waveguide having a non-circular cross section defined in any lateral plane X-Y. In embodiments the core 10 of the waveguide has a very small cross section, which may be smaller than 1 μm. A process to realize this is now described

In order to decrease the fiber diameter during the drawing, we will have to adjust the drawing parameters as the winding rate that will reduce the fiber diameter. In order to do so, both materials, TPU and silicone must be able to be processed at such small geometries. For silicone, that will be quite easy as it will remain liquid and will follow the TPU deformations. If the final fiber diameters are not small enough, it will be possible to start a new drawing process, if silicone has not yet polymerized, in order to reduce the fiber size. This process would be similar as the one proposed in Ref.16 wherein an introduced fiber is melted while a rotating rod coils the microfiber. In our case the melting would be performed by the same heaters that are used to draw the fiber from the preform. Due to the small size of the incoming fiber, not greater than 100 μm, the melting should be achieved rapidly, and the silicone polymerization won't have the time again to happen. Coiling around a rod is mandatory rather than around a normal spool. The reason is that warm TPU fibers will get stuck to each other if they are not cooled enough. For a normal optical fiber drawing, this cooling is performed by taking away the furnace and the winding spool.

In an embodiment a length of useful optical waveguide 1 is determined by cutting it until an acceptable optical transmission is obtained. So, a transmission measurement step may be performed wherein the optical transmission ratio T1/T0 of said short optical waveguide is determined followed by a new step F consisting in cutting another predetermined length of said optical waveguide 1, so as to provide a second short optical waveguide having a length smaller than the length of said first short optical waveguide, said second short optical waveguide having a higher transmission ratio T2/T1 than the transmission ratio T1/T0 of said first short optical waveguide.

In variants, micro or nano-sized optical fibers may be realized. Their diameters may be typically 1 μm, possibly less than 1 μm. In case a preform made of TPE, such as TPU, is filled with UV polymerizable glue or silicone, the liquid that is introduced in the central aperture will follow the deformation of the TPU cylinder during its reduction of diameter so that the central aperture 2002 is not closed during the capillary pulling operation even when micro-sized diameters are reached. Once the predetermined length and outer diameter is reached the internal liquid is polymerized by UV light, through said TPE or TPU.

The invention relates also to a method of fabrication of a system that may be used to realize a Fan-IN/OUT optical system (Ref.17), allowing to connect the outputs and inputs of a multicore fiber (Ref.17), This method comprises preferably the steps of:

-   -   providing a plurality of optical fibers having a non-cured         liquid core and having a diameter typically of 40 μm;     -   aligning the plurality of fibers in a mechanical holder, to form         a bundle, having a plurality of holes and the same fibers         geometry distribution as the multicore fiber. The mechanical         holder has preferably a cylindrical external diameter that is         equal or greater than the multicore fiber to connect;     -   in an embodiment, the number of fibers introduced in the holder         is 7. and may be different types of fiber;     -   gluing the assembly of the mechanical holder, preferably by a UV         glue, in order to fix all components together.

In an embodiment said plurality of optical fibers have a core made at least partially of TPE. In a variant, illustrated in FIG. 17 , the preform is a hybrid preform. For example, a block 4000 may comprise two holders in which wires are arranged (as illustrated in FIG. 16 ) and this structure may be over moulded by a TPE, such as a TPU cladding layer as illustrated in FIG. 17 . The preform 200 may be produced by injection moulding and the first half of the preform constitutes a multicore preform. The second half is a plurality of preferably 7 independent tubes directly aligned and connected to the first part of the preform comprising said two holders.

FIG. 15 shows an example of an arrangement 4000 comprising a portion of a preform comprising two holders 4004, 4004, arranged preferably to realize a fan-in/fan-out optical component.

FIG. 16 shows a portion of a preform comprising two holders of FIG. 15 , to make a fan-in/fan-out optical component, the two holders comprise a plurality of wires 4001 to be removed after injection of a TPE polymer FIG. 16 illustrates two inserts comprising 7 mold cores before injection of the cladding. After overmoulding the volume between the two holders 4002, 4004 and so the wires present in that volume (FIG. 16 ) by a TPE layer 4003. The TPE is then cooled and the wires 4001 are withdrawn, leaving a plurality of axial holes in which another polymer, such as silicone may be introduced. The so formed preform may be drawn to make either a multicore fiber or may be drawn or heated over its central part so as to form a multi-core structure having a central portion with a reduced diameter, which may be used in a Fan-in/Fan-out optical device.

FIG. 18 illustrates the demolding process of such a multicore fiber after the injection of a TPU layer 4003 as cladding layer illustrated in FIG. 17 . FIG. 19 illustrates a multicore Fan-in/Fan-out platform realized with the mold of FIG. 16 and FIG. 17 , and after melting and drawing to reach the final desired diameters. The fan-in/fan-out component 4100 illustrated in FIG. 19 comprises two ends 4104, 4106 having spaced cores and a middle section 4102 wherein the cores are closer than at the two ends 4104 and 4106.

The melt and draw process is realized in the transition area of the hybrid preform in order to decrease the size of the multicore preform part to a normal fiber size and a lower to the normal size for the tubes outgoing from the transition area. In an embodiment the fibers may be arranged in a ring or tube forming a multicore fiber structure-like. This structure is fixed by a thermal flash and then thermally drawn to reach a final diameter equal to the multicore fiber to be connected to.

The invention relates also to an illumination device and method of illumination that is based on the use of varying diameter of the core of a fiber. Such an illumination method comprises the steps of:

-   -   providing an optical waveguide 1 as described herein;     -   introducing light into the core 10 of the optical waveguide 1;     -   stretching portions of the optical waveguide 1 so as to couple         light out of the core 10 to its side and through said cladding         20.

In a variant, the stretching may be made periodically stretched by an automated mechanism. In an embodiment, dopants may be integrated in the TPE cladding layer to provide light diffusion effects by the cladding layer. By integrating dopants, it is possible to make more visible stretched portions of the optical waveguide and so provide lighting effects, useful in for example light decorations.

Experimental Results

a. Realisation of a Fiber with a TPU Core and TPU Cladding

In an exemplary process according to the invention three types of step-index optical fibers with the dimensions listed in Table 1 have been realized. For each fiber its V number has been determined, at three different wavelengths (633 nm, 830 nm and 1300 nm by considering the smallest diameter achieved, and the corresponding estimate of number of modes, by using the equation 1, and a numerical aperture (NA) of 0.38. It was assumed that the NA remains stable with wavelength, e.g., the materials are dispersion free. It may be noticed that the F3 fiber is approaching a few mode fiber (FMF) behaviour for wavelengths >800 nm. The number of modes M is given by equation (1) and depends on the V number which is a dimensionless parameter which is often used in the context of step-index fibers. It is defined as

$V = {{\frac{2\pi}{\lambda}a{NA}} = {\frac{2\pi}{\lambda}a\sqrt{n_{core}^{2} - n_{cladding}^{2}}}}$

where λ is the vacuum wavelength, a is the radius of the fiber core, and NA is the numerical aperture.

$\begin{matrix} {M = {4\frac{V^{2}}{\pi^{2}}}} & (1) \end{matrix}$

TABLE 1 Optical fibers produced Minimal Estimated number core Cladding V number of modes Fiber diameter diameter at λ [nm] at λ [nm] name [μm] [μm] 633 830 1300 633 830 1300 F1 44 199 83.66 63.81 40.73 2′837   1′650   672 F2 10 114 19.01 14.50 9.26 147  85 35 F3 5.4 85 10.27 7.83 4.99 43 25 10

Realized fibers 1 according to the process of the invention have first been visually evaluated under a microscope and white light has been incoupled and guided in fiber lengths of 40 cm. Afterwards, the fibers attenuation was measured using the cut-back technique. Attenuation values obtained, listed in Table 2, are quite similar to those measured for TPU polymer flat sheets except for a 1300 nm wavelength. Attenuation was not measured for the third optical window (e.g. 1550 nm) because of the strong attenuation observed at this wavelength band.

TABLE 2 Optical attenuation of realized TPU fibers produced Attenuation at Attenuation at Attenuation at Fiber 633 nm 830 nm 1300 nm name [dB/cm] [dB/cm] [dB/cm] F1, F2 0.15-0.2 0.1-0.2 0.7-0.8 and F3

A set of sample fibers F3 was used to measure the bending loss and results are shown in FIG. 23 . The fiber F3 was bent on metallic rods with two turns and manually maintained while the power signal was stabilizing. The TPU fibers are so soft that any touch makes a direct stress on the core-cladding interface and thus a variation in the optical transmission when fiber is bent. Additionally, to bend the fiber around a rod, there is inevitably a non-negligible elongation of the fiber which induce an additional loss. However, the fibers may be well used for short lengths in applications where small bend radius are needed.

The variation of transmitted intensities of the optical waveguide 1 can be used to realize a pressure sensor or a system in which the transmitted intensity varies according to applied pressure or bending. FIG. 22 shows experimental results of variations of intensity b using a 8 cm length of a fiber made of a TPU core and TPU cladding by adhering the fiber to the outside surface of an inflatable balloon. FIG. 22 shows the variations in detected intensities by inflating the balloon. The fiber underwent a variation in length of up to 30%. The dimension of the core changed by 30%, from initially 10 μm to 6.6 μm. The wavelength used was 633 nm. FIG. 24 illustrates the change of the number of modes in function of the elongations that the fiber underwent and are expressed in %. The initial length is illustrated by 0% and 128% means the length has increased by a factor of 2.28.

b. Realisation of a Fiber with a TPU Cladding and a Silicone Core

In an experimental process according to the invention, a TPU based capillary is filled with silicone to realize an optical fiber. In such process of a TPU capillary 2000, the first step is to produce a cladding preform 200, preferably by injection moulding. The cladding dimensions has to respect the ratio of the final cladding diameter and core fiber diameter in order to obtain a multimode fiber having a predetermined number of guides modes, or to ensure a fiber and core size that may be close to or equal to standard single mode fibers. The cladding diameter must comply with the moulding dimension constrains but also depends on the initial central hole diameter that is needed to use an insert inside the mould. This insert is a critical component of the cladding production as it can be crooked by the hot polymer flow during the moulding process. Based on these constraints and typical injection moulding equipment, typical cladding diameters are up to 20 mm for a length of about 100 mm. The central hole diameter of the preform 200 is normally not less than 1 mm because of the polymer flow stress during moulding. Hole diameters of the preform as low as 0.5 mm may be obtained. Another constraint on the insert is its surface quality and adherence to the TPU. The surface quality will directly influence the optical interface between TPU and silicone, and fortiori, the optical guidance losses inside the final fiber. Thus, a surface treatment is in principle needed in order to reduce the roughness and the TPU adherence. Once the cladding preform is obtained, a standard process of thermal fiber drawing provides a hair thin TPU fiber capillary. Because the lengths of fiber that are needed for most applications addressed here, are quite short (10-15 cm), the conicity and diameter fluctuations are less constricting and hence relax the process constraints.

Tests have been performed to realize silicone penetration in small diameter capillaries, glass capillaries 2000 are used having a central hole 2002 of 15 μm and external diameter of 125 μm. By using the syringe technique, it is possible to inject silicone in a length of around 100 mm. By using vacuum pump techniques together with a syringe, it is possible to achieve a penetration depth of more than 100 mm. By modifying the wettability of the inner capillary walls, hence with the help of the capillary filling force, the initial penetration length is improved. In addition, by using more performant vacuum pumps, and by increasing the syringe efficiency on the other side of the fiber, penetrations depths over fiber lengths up to 20-40 cm are achievable.

In a typical silicone-based optical fiber the core material is made of a silicone that is usually used as a LED liquid encapsulant. The silicone is an OPTOLINQ trademark OLS-5291-type silicone commercialized by Caplinq Corporation (Canada).

The cladding material was a TPU polymer that can be found at very soft grades, such as the BASF 1185A TPU. Achieved cladding dimension may be 200 μm and the core diameter 50 μm and the length of the fiber 1 may be at least 250 mm. The fiber has a typical a high numerical aperture of 0.32. Typical realized fibers may be stretched by about 50%, i.e. elongating the optical fiber up to 375 mm without notable optical losses. Bending losses were less than 20-30% due to the high numerical aperture of the fiber 1. This cannot be achieved by other polymer-based fibers of prior art such as PMMA fibers. Tests have shown that squeezing an optical fiber 1 of the invention does not alter its mechanical or optical properties. For example, by applying a lateral force of 20 N-30 N the optical fiber returns to its initial shape without any changes of its mechanical or optical properties.

Typical optical transmissions of the optical waveguide 1, measured by an optical bench are:

-   -   at 633 nm the attenuation was 0.2-0.3 dB/cm;     -   at 1300 nm the attenuation was: 0.3-0.5 dB/cm;     -   at 1550 nm a typical attenuation was 0.6-0.9 dB/cm.

The optical waveguide 1 of the invention may be used for some UV applications, if the lengths are typically shorter than 100 mm. In the UV, estimates of transmission were about 30-60% at 300 nm for a length of 50 mm, but the transmission value may vary considerably according to the type of polymers that are used and of course of the UV wavelength, Transmissions below 300 nm are typically lower than 20-10% for lengths of fiber of about 50 mm.

Applications of the Waveguide 1 of the Invention

One of the important applications of the optical waveguide of the invention 1 relates to implants and more specifically cochlear implants. For such applications the 3D printing of the TPU-based preform as described herein is particularly well adapted. The optical waveguide 1 has been implemented in a pressure sensor tip arranged at a cochlear implant tip. The optical waveguide 1 is intended to minimize accidental structural intracochlear damage. Recent studies have demonstrated pressure pulses equivalent to sound levels causing severe impulse trauma during implantation, caused by the insertion of the electrode array into the enclosed space of the cochlea. A solution implementing the optical waveguide 1 of the invention will improve surgery reliability and flexibility and also the implant quality by avoiding any failure during the critical process of implantation. A cochlear implant cost, including surgery, can vary between USD 30'000-50'000. A failed surgery, though rare, will induce a second surgery preceded by a patient recovery time whilst an implant dysfunction (due to structural damage) is potentially possible as well. Additionally, the residual structures and neural tissue in the cochlea are highly relevant to the sound quality experienced by the patient. The insertion process can be highly traumatic to these structures, due to pressure pulses caused by surgeon handling and penetration of important membranes. Novel optical fiber technologies may revolutionize the surgical procedure, reducing fibrotic tissue growth and also maintaining the cochlear condition for successful future regenerative therapies to enhance the outcome. Furthermore, implantable optical technology could also improve the post-operative rehabilitation by continuously monitoring physiological parameters. The optical waveguide of the invention allows to decrease dramatically implants failures as well as surgery failures by providing a feedback measurement of important physiological or environmental parameters. Furthermore, it opens the door for long term and highly localized monitoring of physiological parameters. This is of high interest as it will enable to make an early detection of medical issues, enabling in this way to minimize possible post-implantation traumas and their consequent surgeries. It is also providing a solution to diminish wastes by increasing the reliability of implants and the consumables needed for surgeries. Subsequently, the potential diminution of wastes is obviously enhancing the energy efficiency of the implantation activities by reducing the implantation failures and their possible traumas but as well by preventing important surgeries on a long-term point of view.

Other important applications that may profit from the optical waveguide 1 of the invention are, but not exclusively:

-   -   ophthalmology: a pressure sensing device using the optical         waveguide 1 is useful in cataract surgery;     -   spinal traumatology: Pressure monitoring after surgery (vertebra         or disc replacement);     -   heart traumatology: blood flow and pressure monitoring after a         heart attack, localized micro-surgery;     -   cardiac surgery, orthopedics, urology, and neurology;     -   security and counterfeit applications;     -   industrial sensor applications.

As a totally new class of optical waveguides, different applications of the waveguide of the invention could generate new markets. As an example, Bragg gratings may be provided on the TPU-based waveguide 1 to improve its sensitivity with no need of any additional sensor. The optical waveguide 1 of the invention can be used for sensing, as explained for implants manufacturers, but could also be used to bring light at remote locations where glass optical fibers would be hazardous to use. The optical waveguides 1 of the invention may also be used in FAN/IN-FAN/OUT systems, such as for example described in Ref.15.

Still other applications address decorative illumination devices. A TPE such as TPU cladding may be doped with diffusing particles. In an example, light may be made more or less visible in sections where the core has a reduced size by pulling a section of the optical waveguide. In other applications Bragg gratings may be arranged on the optical waveguide 1 of the invention and allow to replace for example SiO2-based optical waveguides or fibers. Such waveguides 1 may be used for cryogenic applications where the thermal dilation of SiO2 is substantially non existing.

BACK-GROUND INFORMATION AND REFERENCES

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1. An optical waveguide, comprising at least one core, defining a longitudinal axis Z, and a cladding surrounding said core, said core and said cladding being configured to transmit along said longitudinal axis Z a light beam having a wavelength greater than 180 nm, said at least one core comprising at least an outermost layer and said cladding comprising at least an innermost layer in contact with the outermost layer of the core, wherein said outermost layer of the core is made of a material having a first index of refraction, said innermost layer of the cladding is made at least partially of a thermoplastic elastomer having a second index of refraction being smaller than said first index of refraction.
 2. The optical waveguide according to claim 1 wherein said thermoplastic elastomer is chosen among: a thermoplastic polyurethane, a styrenic block copolymer, a thermoplastic polyolefin elastomer, thermoplastic Vulcanizate, a thermoplastic copolyester, a thermoplastic polyamide or a not classified thermoplastic elastomer.
 3. The optical waveguide according to claim 1, wherein said cladding comprises at least one additional layer made of a thermoplastic elastomer chosen among: a thermoplastic polyurethane, a styrenic block copolymer, a thermoplastic polyolefin elastomer, a thermoplastic Vulcanizate, a thermoplastic copolyester, a thermoplastic polyamide or a not classified thermoplastic elastomers.
 4. The optical waveguide according to claim 1, wherein said core is made, at least partially, of a thermoplastic elastomer chosen among: a thermoplastic polyurethane, a styrenic block copolymer, a thermoplastic polyolefin elastomer, a thermoplastic Vulcanizate, a thermoplastic copolyester, a thermoplastic polyamide or not classified thermoplastic elastomers.
 5. The optical waveguide according to claim 1, wherein said core is made, at least partially, of silicone.
 6. The optical waveguide according to claim 1, wherein said core has an index of refraction smaller than 1.5.
 7. The optical waveguide according to claim 1, wherein the inner surface of said cladding comprises a metallic and/or a dielectric layer arranged to reflect light that is incoupled into said core.
 8. The optical waveguide according to claim 1, wherein the optical waveguide is an optical fiber.
 9. The optical waveguide according to claim 1, having a first lateral side having a first width and a second side having a second width larger than said first width, said widths being defined in any lateral cross section, defined in an plane orthogonal to said longitudinal axis Z.
 10. The optical waveguide according to claim 1, having a smallest dimension of said core of less than 10 μm, or less than 5 μm, or less than 2 μm.
 11. The optical waveguide according to claim 10, wherein the optical waveguide is a monomode optical waveguide.
 12. The optical waveguide according to claim 1, wherein the optical waveguide is a tapered optical waveguide having at least two different cross sections.
 13. The optical waveguide according to claim 1, wherein the optical transmission, defined as the ratio of the intensity of the outcoupled light to the intensity of the incoupled light is greater than 50%, for incoupled light having wavelengths between 180 nm and 25 μm, said optical waveguide having a length smaller than 1 m or smaller than 50 cm.
 14. The optical waveguide according to claim 13, wherein said optical transmission, is greater than 80% for incoupled light having wavelengths between 300 nm and 5 μm.
 15. The optical waveguide according to claim 1, configured to be elastically stretchable up to at least 10% of the optical waveguide's length and so that, after having been stretched, the optical transmission remains at least 90% of the transmission of the optical waveguide before being stretched.
 16. The optical waveguide according to claim 1, comprising at least two cores.
 17. The optical waveguide according to claim 16, comprising at least six cores.
 18. An optical waveguide bundle comprising at least three optical waveguides according to claim
 1. 19. A medical device comprising at least one optical waveguide according to claim
 1. 20. The medical device according to claim 19, wherein said device is a cochlear implant device.
 21. An optical sensor comprising at least one optical waveguide according to claim 1 and an optical cavity sensor head arranged to said optical waveguide, the sensor head comprising an optical cavity closed by a flexible membrane.
 22. A pressure sensor comprising at least at least one optical waveguide according to claim
 1. 23. A mechanical elongation sensor comprising at least at least one optical waveguide according to claim
 1. 24. A method of fabrication of an optical waveguide according to claim 1, comprising the steps of: A. Realizing a hollow shaped preform which will form the cladding of the optical waveguide, the hollow shaped preform comprising an innermost layer made at least partially of a thermoplastic elastomer having a second refractive index, and a central aperture; B. Filling the central aperture of said hollow shaped preform so as to produce the core part of the preform which will form the core of the optical waveguide, said core part comprising an outermost layer having a first index of refraction being higher than said second index of refraction, said innermost layer being formed in contact with said outermost layer, so as to provide a filled preform; and C. reducing the diameter of said filled preform and elongating said filled preform to obtain an optical waveguide having a predetermined length L and a predetermined cross section.
 25. The method of fabrication of an optical waveguide according to claim 24 wherein said thermoplastic elastomer is a thermoplastic polyurethane.
 26. The method according to claim 24, wherein the central aperture of the hollow shaped preform is filled with a thermoplastic elastomer chosen among a thermoplastic polyurethane, a styrenic block copolymer, a thermoplastic polyolefin elastomer, a thermoplastic Vulcanizate, a thermoplastic copolyester, a thermoplastic polyamide or a not classified thermoplastic elastomer.
 27. A method of fabrication of an optical waveguide according to claim 1, comprising: realizing a hollow shaped preform which will form the cladding of the optical waveguide, the hollow shaped preform comprising an innermost layer made at least partially of a thermoplastic elastomer having a second refractive index, and a central aperture; reducing the diameter of said hollow shaped preform and elongating the hollow shaped preform until a capillary is formed having a predetermined length and a predetermined cross section, said capillary having a central aperture having a predetermined cross section; introducing liquid silicone into the central aperture of said hollow shaped preform; and polymerising said liquid silicone so as to form an optical waveguide having a core being made of polymerised liquid silicone.
 28. A method of fabrication of an optical waveguide according to claim 1, comprising: realizing a hollow shaped preform which will form the cladding of the optical waveguide, the hollow shaped preform comprising an innermost layer made at least partially of a thermoplastic elastomer having a second refractive index, and a central aperture; reducing the diameter of said hollow shaped preform and elongating the hollow shaped preform until a capillary is formed having a predetermined length and a predetermined cross section, said capillary having a central aperture having a predetermined cross section; introducing liquid silicone during said step B′ of reducing the diameter of said hollow shaped preform; while reducing the diameter of said hollow shaped preform keeping said liquid silicone in a liquid state until a predetermined length and a predetermined cross section of a precursor optical waveguide is obtained; and thermal polymerising said liquid silicone and said capillary so as to form an optical waveguide.
 29. A method of fabrication of an optical waveguide according to claim 1, comprising: realizing a hollow shaped preform which will form the cladding of the optical waveguide, the hollow shaped preform comprising an innermost layer made at least partially of a thermoplastic elastomer having a second refractive index, and a central aperture; after realizing a hollow shaped preform, introducing a liquid polymer into the central aperture of said hollow shaped preform so as to provide a filled preform; reducing the diameter of the filled preform filled with liquid polymer and elongating said filled preform until a capillary is formed filled with liquid polymer, said capillary having a predetermined length and a predetermined cross section; and polymerising said liquid polymer by applying UV light.
 30. The method according to claim 29 wherein said liquid polymer is liquid silicone.
 31. The method of fabrication according to claim 24, wherein to said hollow shaped preform at least one additional layer is arranged, said additional layer being made of a thermoplastic elastomer layer chosen among a thermoplastic polyurethane, a styrenic block copolymer, a thermoplastic polyolefinelastomer, a thermoplastic Vulcanizate, a thermoplastic polyurethane, a thermoplastic copolyester, a thermoplastic polyamide or a not classified thermoplastic elastomers, said thermoplastic elastomer being defined according to the ISO norm
 18064. 32. The method according to claim 24, wherein said preform is made in TPU by a 3D printing technique.
 33. The method according to claim 32 wherein said preform is made so as to comprise at least 6 apertures and providing a multicore optical waveguide having at least 6 cores.
 34. The method according to claim 24, wherein said preform and said optical waveguide is made so that the optical waveguide has a non-uniform cross section over a predetermined length, the cross section being defined orthogonal to the length of the preform, respectively the optical waveguide.
 35. A method of fabrication of an optical waveguide according to claim 1, comprising the steps of: A″. realizing a preform made entirely by a 3D printing technique, said preform comprising a core part which will form the core of the optical waveguide and an outer part which will form the cladding of the optical waveguide, B″. elongating said preform to obtain an optical waveguide having a predetermined length L and a predetermined cross section.
 36. The method according to claim 35, wherein the core part and the outer part of the preform are realized by 3D printing of successive layers, each of the successive layers comprising a central portion and an outer portion, the central portion having, at least to the central portion's side of said outer portion, a first index of refraction, said outer portion being made, at least to the outer portion's side of said inner portion, at least partially of a thermoplastic elastomer having a second index of refraction being smaller than said first index of refraction.
 37. The method according to claim 36, wherein the central portions and the outer portions of the successive layers are made, at least partially, of a thermoplastic elastomer chosen among a thermoplastic polyurethane, a styrenic block copolymer, a thermoplastic polyolefinelastomer, a thermoplastic Vulcanizate, a thermoplastic copolyester, a thermoplastic polyamide or a not classified thermoplastic elastomer.
 38. The method according to claim 36, wherein at least two of said successive layers are different shaped layers or layers having a different material composition.
 39. The method of fabrication according to claim 35, wherein to said preform at least one additional layer is arranged, said additional layer being made of a thermoplastic elastomer layer chosen among a thermoplastic polyurethane, a styrenic block copolymer, a thermoplastic polyolefin elastomer, a thermoplastic Vulcanizate, a thermoplastic polyurethane, a thermoplastic copolyester, a thermoplastic polyamide or a not classified thermoplastic elastomers, said thermoplastic elastomer being defined according to the ISO norm
 18064. 40. A method of performing a chirurgical operation, comprising providing the optical waveguide of claim 1, providing a chirurgical instrument, and utilizing the optical waveguide and the chirurgical instrument to perform the chirurgical operation.
 41. The method of claim 40, further comprising tracking of the localisation of a position of said chirurgical instrument and/or the tracking of optical properties of tissues in the neighbourhood of a tip of said chirurgical instrument. 